調查員天賦下列的天賦有助於追逐使毒藝術的調查員們。叛道毒物(Anathema，Ex)：當調查員創造或準備一件毒藥時，這也包含起源自種族或職業能力的毒藥，他可以花費1點靈感點來創造一件叛道毒物。叛道毒物也是毒藥，但它可以影響通常會免疫毒藥的生物，他們利用其本質上的弱點而非生物性。當創造一件叛道毒物後，從遊俠宿敵表中選擇一個生物類別(或子類，如果適用的話)；該叛道毒物將只作用於對抗被揀選的生物類別。調查員也要選擇一樣下列的特殊能力，叛道毒物將影響該樣能力：傷害減免(除了DR/─)、能量抗力(由調查員選擇一種能量類別)、快速痊癒、移動速度或法術抗力。
傳遞毒物的方法(接觸、攝入、吸入或傷口)以及叛道毒物的豁免DC與用來製作叛道毒物的毒藥相同。如果目標對抗叛道毒物的豁免失敗(即便該敵人正常來說免疫那需要特定豁免的效果，例如不死生物會免疫需要進行強韌豁免的效果)，所選擇能力的數值會降低5(最小為0)，持續1輪/調查員等級。
高等叛道毒物(Greater Anathema，Ex)：調查員的叛道毒物，對能力的削減增加至10，並且他可以將DR/─以及再生加入他可以靠叛道毒物降低的能力列表中。此外，當調查員創造一件叛道毒物時，他可以指定一個特定種類的生物(像是吸血鬼)，而不是一個生物類別。當使用叛道毒物對抗該特定敵人時，叛道毒物的豁免DC會較原材料毒藥高2。
調查員必須擁有叛道毒物調查員天賦後才能選擇此天賦。殘存毒液(Lingering Venom，Ex)：調查員個人應用到武器與陷阱，或以其他方式施加於敵人上的毒藥，需要額外一次成功的豁免檢定來治癒。
調查員必須要至少5級才能選擇此專長。原文
劇透 - :
Anathema (Ex): When an investigator creates or prepares a poison, including poisons derived from racial or class abilities, he can spend one use of inspiration to create an anathema instead. Anathemas count as poisons, but they can affect creatures that are normally immune to poison, as they exploit vulnerabilities in their very nature rather than their biology. When an anathema is created, select a creature type (and subtype, if applicable) from the ranger favored enemy list; the anathema functions only against this chosen type. The investigator also chooses one of the following special abilities for the anathema to affect: damage reduction (except DR/—), energy resistance (one type chosen by the investigator), fast healing, movement speed, or spell resistance.
The method of delivery (contact, ingested, inhaled, or injury) and the DC of the anathema’s save are identical to those of the poison used to make the anathema. If the target fails its save against the anathema (even if the enemy is normally immune to effects that require a specific save, such as undead’s immunity to effects that require a Fortitude save), the value of the chosen ability is lowered by 5 (minimum 0) for 1 round per investigator level.
Greater Anathema (Ex): The ability reduction of the investigator’s anathemas increases to 10, and he adds DR/— and regeneration to the list of abilities he can lower with an anathema. In addition, when an investigator creates an anathema, he can designate a specific kind of creature (such as vampires) in addition to the creature type. When used against this specific foe, the DC of the save against the anathema is 2 higher than the component poison. An investigator must have the anathema investigator talent to select this talent.
Lingering Venom (Ex): Poisons that the investigator personally applies to weapons and traps, or otherwise inflicts upon foes, require one additional successful save to cure. An investigator must be at least 5th level to select this talent.
